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Biochemistry of Alzheimer’s Disease |
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Alzheimer's Disease is one of the common diseases in today's world. It is one of the diseases which affects a large number of people from all over the world especially who are 65 years of age. The chances of affecting with this disease increases if a person is more than 70 years of age. This is one of the diseases in which the person looses his or her memory. One of the common causes of the adult dementia is known to be the biochemistry of Alzheimer's Disease. But again it should be noted that the molecular levels of the biochemistry of Alzheimer's Disease is not known.
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The biochemistry of Alzheimer's Disease has been identified as a protein misfolding disease as well. The protein is misfolded because of the abnormal accumulation of the amyloid beta protein. This is mostly found in the brains of the patients of Alzheimer's Disease. There are various other things involved in the Biochemistry of Alzheimer’s Disease. Some of them are noted below. Have a look to know more:
Neuropathology- This is one of the major parts of the Biochemistry of Alzheimer’s Disease. This is one of the situations in which the doctor comes to know more about the the neurobirillary tangles as well as the amyloid flaques. This can also be known as the help of a microscopy of the brains of the Alzheimer's disease. This will also help the doctors to judge the patients condition. From this the doctors also come to know about the temporal lobe as well as the parietal lobe. This will also help you in knowing the condition of the frontal cortex and the cingulate gyrus.
Cholinergic Hypothesis- This is also a major part of the Biochemistry of Alzheimer’s Disease. This is also one of the oldest hypothesis in this field. This is one of the hypothesis which states that Alzheimer's disease starts because of the deficiency of the formation of the acetylcholine. This is one of the important neurotransmitter. Most of the earlier medicines of the Alzheimer's disease has been developed on the basis of this hypothesis. But again the results have come up to be dicey because at times this medicines have been of great help to the patients but again in case of some patients, these medicines are not affective at all.
Tau Hypothesis: This is another important hypothesis in case of biochemistry of Alzheimer's Disease. According to this hypothesis, it is tau which is one of the important causes of the Alzheimer's Disease. The presence of various other diseases all support the tau hypothesis. But most of the researchers as well as the doctors believe that amyloid is the main cause of the disease.
Amyloid Hypothesis: This is also an important part of the Biochemistry of Alzheimer’s Disease. This is one of the widely accepted theories as well. This is one of the hypothesis which is also related with the Down Syndrome. This is one of the hypothesis is a;sp supported by a large number of people.
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